Methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate: Kayayyaki da Ayyuka

Methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylatemahadi ne na sinadarai tare da tsarin kwayoyin C9H6F2O4 da lambar CAS 773873-95-3. Hakanan an san shi da ma'ana da yawa, irin su methyl 2,2-difluoro-1,3-benzodioxole-5-carboxylate, 2,2-difluorobenzodioxole-5-carboxylic acid methyl ester, da EOS-61003. Yana cikin ajin heterocyclic mahadi tare da oxygen hetero-atoms kawai.

Boasting a tsarki na 98% m, wannan Pharmaceutical-sa fili ne mai m bayani ga masana'antu kamar Pharmaceuticals, agrochemicals, da kuma bincike.Wannan fili da ake amfani da matsayin key matsakaici a Pharmaceutical kira, halittar amfanin gona kariya kayayyakin, da kuma kimiyya bincike.

A cikin wannan labarin, za mu bayyana cikakkun kaddarorin samfurin da aikin methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate, dangane da bayanan da ake samu.

Abubuwan Jiki da Sinadarai

Methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate ruwa ne mara launi zuwa kodadde rawaya ko daskararru, dangane da zafin jiki da tsabta. Yana da nauyin kwayoyin halitta na 216.14 g/mol da yawa na 1.5±0.1 g/cm3. Yana da wurin tafasa na 227.4±40.0 °C a 760 mmHg da madaidaicin walƙiya na 88.9±22.2 °C. Yana da ƙananan matsa lamba na 0.1± 0.4 mmHg a 25 ° C da ƙarancin ruwa na 0.31 g / L a 25 ° C. Yana da darajar log P na 3.43, yana nuna cewa ya fi narkewa a cikin kaushi mai ƙarfi fiye da ruwa.

Tsarin methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate ya ƙunshi zoben benzene da aka haɗa tare da zoben 1,3-dioxole, tare da ƙwayoyin fluorine guda biyu da ƙungiyar carboxylate da ke haɗe zuwa zoben benzene. . Kasancewar atom ɗin fluorine yana ƙaruwa da kwanciyar hankali da haɓakawa na fili, kazalika da lipophilicity da bioavailability. Ƙungiyar carboxylate na iya aiki azaman ƙungiyar barin ko nucleophile a cikin halayen daban-daban. Zoben 1,3-dioxole na iya aiki azaman glycol mai rufe fuska ko dienophile a cikin halayen cycloaddition.

Tsaro da Gudanarwa

Methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate an rarraba shi azaman abu mai haɗari bisa ga Tsarin Tsarin Rarrabawa da Lakabi na Sinadarai (GHS). Yana da maganganun haɗari da maganganun kariya masu zuwa:

• H315: Yana haifar da haushin fata

• H319: Yana haifar da tsananin haushin ido

H335: Zai iya haifar da haushin numfashi

P261: Guji ƙurar numfashi / hayaƙi / gas / hazo / tururi / fesa

• P305+P351+P338: IDAN A IDO: Kurkura da ruwa a hankali na tsawon mintuna da yawa. Cire ruwan tabarau na lamba, idan akwai kuma mai sauƙin yi. Ci gaba da kurkure

• P302+P352: IDAN A FATA: A wanke da yawan sabulu da ruwa

Matakan taimakon farko na methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate sune kamar haka:

• Inhalation: Idan an shaka, matsar da mara lafiya zuwa iska mai kyau. Idan numfashi yana da wahala, ba da iskar oxygen. Idan ba numfashi ba, ba da numfashi na wucin gadi. Samun kulawar likita

• Tuntuɓar fata: Cire gurɓataccen tufafi da kurkura fata sosai da sabulu da ruwa. Idan kun ji rashin jin daɗi, nemi kulawar likita

• Tuntuɓar idanu: Rarrabe gashin ido kuma kurkura da ruwan gudu ko gishiri na yau da kullun. A nemi kulawar likita nan take

• Ciki: Gargaɗi, kar a jawo amai. A nemi kulawar likita nan take

Matakan kariyar wuta don methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate sune kamar haka:

• Wakilin kashewa: Kashe wuta da hazo na ruwa, busassun foda, kumfa ko carbon dioxide mai kashewa. A guji amfani da ruwa mai gudu kai tsaye don kashe wutar, wanda zai iya haifar da zubar da ruwa mai ƙonewa da kuma yada wutar.

• Hatsari na musamman: Babu bayanai da akwai

Kariyar wuta da matakan kariya: Ya kamata ma'aikatan kashe gobara su sa na'urorin numfashi na iska, su sa cikakkun tufafin wuta, kuma su yi yaƙi da iska. Idan zai yiwu, matsar da kwandon daga wuta zuwa wuri mai buɗewa. Dole ne a kwashe kwantena a yankin wuta nan da nan idan sun canza launin ko fitar da sauti daga na'urar agajin aminci. Ware wurin da hatsarin ya faru kuma ka hana ma'aikatan da ba su da mahimmanci shiga. Ya ƙunshi da kuma kula da ruwan wuta don hana gurɓacewar muhalli

Kammalawa

Methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate shine mabuɗin tsaka-tsaki a cikin haɗin magunguna, ƙirƙirar samfuran kariyar amfanin gona, da binciken kimiyya. Yana da tsari na musamman tare da ƙwayoyin furotin guda biyu da ƙungiyar carboxylate da aka haɗe zuwa zoben benzodioxole, wanda ke ba da kwanciyar hankali, reactivity, lipophilicity, da bioavailability zuwa fili. Yana da ƙarancin solubility na ruwa da matsa lamba, da matsakaicin wurin tafasa da filasha. An rarraba shi azaman abu mai haɗari kuma yana buƙatar kulawa da kyau da adanawa. Yana da m aikace-aikace a daban-daban masana'antu, kamar Pharmaceuticals, agrochemicals, bincike, da sauransu.

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