Praziquantel

samfur

Praziquantel

Bayanan asali:

Praziquantel wani fili ne na kwayoyin halitta tare da tsarin sinadarai C 19 H 24 N 2 O 2 . Ana amfani da anthelmintic a cikin mutane da dabbobi. Ana amfani da shi musamman don magance tsutsotsi da mura. Yana da tasiri musamman akan schistosoma japonicum, ciwon hanta na kasar Sin, da Diphyllobothrium latum.

Tsarin sinadaran: C 19 H 24 N 2 O 2

Nauyin Kwayoyin: 312.406

Lambar CAS: 55268-74-1

Lambar EINECS: 259-559-6


Cikakken Bayani

Tags samfurin

Physicochemical dukiya

Girma: 1.22 g/cm3
Matsayin narkewa: 136-142°C
Tushen tafasa: 544.1°C
Matsakaicin walƙiya: 254.6°C
Fihirisar magana: 1.615
Bayyanar: Fari ko kashe-fari crystalline foda

amfani

An fi amfani dashi azaman maganin antiparasitic mai fadi don jiyya da rigakafin schistosomiasis, cysticercosis, paragonimiasis, echinococcosis, fasciococcus, echinococcosis, da cututtukan helminth.

Halaye

Wannan samfurin fari ne ko fari-farin lu'u-lu'u.
Wannan samfurin yana da sauƙin narkewa a cikin chloroform, mai narkewa a cikin ethanol, kuma maras narkewa a cikin ether ko ruwa.

Wurin narkewa

Matsakaicin narkewa na wannan samfur (Rule na Gabaɗaya 0612) shine 136 ~ 141℃.

category

Anthhelmintics.

Alamomi

Yana da faffadan magani ga trematodes da tepeworms. Ya dace da schistosomiasis daban-daban, clonorchiasis, paragonimiasis, fasciolosis, cutar tapeworm da cysticercosis.

Ayyukan Pharmacological

Wannan samfurin yafi haifar da gurɓataccen ɓarna da zubar da schistosomes da tapeworms a cikin rundunar ta hanyar tasirin 5-HT. Yana da tasiri mai kyau akan mafi yawan manya da tsutsotsi marasa girma. A lokaci guda, yana iya rinjayar haɓakar ƙwayar calcium ion a cikin ƙwayoyin tsoka na jikin tsutsa, ƙara yawan kwararar ions na calcium, hana sake dawowa na sarcoplasmic reticulum calcium famfo, yana ƙara yawan abun ciki na calcium ion a cikin ƙwayoyin tsoka na tsutsa. jiki, kuma ya sa jikin tsutsotsi ya shanye ya fadi.

Adanawa

Ka nisanci haske kuma adana a cikin akwati da aka rufe.


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