Sulfamethazine

Sulfadiazine maganin rigakafi ne na sulfanilamide mai irin wannan nau'in bakan na kashe kwayoyin cuta zuwa sulfadiazine. Yana da tasirin kashe kwayoyin cuta akan kwayoyin enterobacteriaceae irin su Staphylococcus aureus ba-zymogenic, Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, Klebsiella, Salmonella, Shigella, da sauransu. Duk da haka, juriya na ƙwayoyin cuta ga samfurin ya karu, musamman streptococcus, Neisseria da Enterobacteriaceae kwayoyin. Sulfonamides sune manyan jami'ai na bacteriostatic, kama a cikin tsari zuwa p-aminobenzoic acid (PABA), wanda zai iya yin gasa a kan dihydrofolate synthetase a cikin kwayoyin cuta, don haka yana hana PABA daga amfani da shi azaman albarkatun kasa don haɗa folate da ake buƙata ta ƙwayoyin cuta da rage yawan adadin. tetrahydrofolate mai aiki da metabolism. Ƙarshen abu ne mai mahimmanci don haɗuwa da purines, thymidine nucleosides da deoxyribonucleic acid (DNA), don haka yana hana ci gaba da haifuwa na kwayoyin cuta.