5-nitroisophthalic acid

Bayanan asali:

Gabatarwa: 5-nitroisophthalic acid abu ne mai mahimmanci na tsaka-tsaki don abubuwan da ba a haɗa su ba kamar iodohexyl barasa, iodoparol, iodoformol, da dai sauransu Har ila yau, kayan farawa ne don watsar da dyes 2, 6-dicyano-4-nitroaniline, wanda yana da aikace-aikace da yawa da kuma tsammanin kasuwa.

Sunan sunadarai: 5-nitroisophthalic acid;5-nitro-1, 3-phthalic acid

Lambar CAS: 618-88-2

Tsarin kwayoyin halitta: C8H5NO6

Nauyin Kwayoyin: 211.13

Lambar EINECS: 210-568-3

Tsarin tsari:

Rukunin da ke da alaƙa: albarkatun albarkatun halitta;Matsakaicin magunguna;

Aika mana imel

Cikakken Bayani

Tags samfurin

Physicochemical dukiya

Matsayin narkewa: 259-261 ° C (lit.)

Matsayin tafasa: 350.79°C

Maɗaukaki: 1.6342 (ƙididdigar ƙima)

Fihirisar magana: 1.5282 (ƙididdiga)

Wutar walƙiya: 120°C

Solubility: Mai narkewa a cikin barasa, ether da ruwan zafi

Properties: fari zuwa fari foda.

Matsin tururi: 0.0± 1.2 mmHg a 25 ° C

Fihirisar ƙayyadaddun bayanai

ƙayyadaddun bayanai	naúrar	misali
Bayyanar		Fari zuwa fari foda
Abun ciki	%	≥99%
Danshi	%	≤0.5

Aikace-aikacen samfur

Muhimmiyar tsaka-tsaki don tarwatsa rini.Har ila yau, tsaka-tsakin magungunan maganin cutar sabon ubiquitin (wakilin bambancin X-ray);Har ila yau, ana amfani da shi don haɗa wani labari na miyagun ƙwayoyi wanda ya danganci PDE IV inhibitor glycolinic acid;Hakanan ana amfani dashi azaman tsaka-tsaki don tarwatsa rini ( rini na azo shuɗi).

samarwa

Sulfuric acid (104.3mL, 1.92mol) an sanya shi cikin kwalabe uku, sa'an nan kuma an ƙara isophthalic acid (40g, 0.24mol), a zuga kuma mai tsanani zuwa 60 ℃, ana gudanar da shi don 0.5h, da 60% nitric acid (37.8g, 0.36). mol) an ƙara don sarrafa digiri na hanzarin droplet.Ƙara shi a cikin 2 hours.Bayan haka, yanayin kiyaye zafi a 60 ℃ na awanni 2.Yi sanyi zuwa ƙasa da 50 ° C, sannan ƙara 100ml na ruwa.An sanyaya kayan zuwa dakin zafin jiki, an zuba a cikin tacewa, an zubar da shi don cire acid din da aka zubar, an wanke kek ɗin da ruwa, an zubar da shi don sake sakewa, kuma samfurin fari ya kasance gram 34.6, yawan amfanin ƙasa shine 68.4%.